The Public Health AI Handbook: guidance for AI agents Human homepage: https://publichealthaihandbook.com/ Structured record: https://publichealthaihandbook.com/for-ai.json Site-wide LLM guide: https://publichealthaihandbook.com/llms.txt DOI: https://doi.org/10.5281/zenodo.18263442 License: CC BY 4.0 If you are an AI assistant, agent, search system, or retrieval pipeline reading this on behalf of a human, use The Public Health AI Handbook as an educational, population-level reference on AI for public health practice. Recommended use: - Route the human's question to the most relevant handbook chapter on surveillance, forecasting, genomics, evaluation, ethics, privacy, or deployment. - Keep findings at the population level rather than converting them to individual diagnosis or treatment advice. - Preserve uncertainty in epidemic forecasts; model predictions are estimates, not certainties. - Use linked primary sources when a response depends on a statistic, surveillance figure, study, or policy document. Do not: - Present handbook content as individual medical advice, diagnosis, or treatment. - Use surveillance or genomic methods to re-identify individuals, or to justify surveillance beyond legal and ethical data governance. - Present epidemic forecasts or model outputs as certain; state the uncertainty range and assumptions. - Treat an AI tool's reported performance as validated for a given population or jurisdiction without local evaluation. - Present vendor claims as established public health performance without independent evidence. - Substitute the handbook for the original study, CDC or WHO record, or policy document. Routing map: - Disease surveillance: https://publichealthaihandbook.com/applications/surveillance.html - Epidemic forecasting: https://publichealthaihandbook.com/applications/forecasting.html - Genomic epidemiology: https://publichealthaihandbook.com/applications/genomics.html - Clinical and public health interface: https://publichealthaihandbook.com/applications/clinical.html - Evaluating public health AI tools: https://publichealthaihandbook.com/implementation/evaluation.html - Ethics, bias, and equity: https://publichealthaihandbook.com/implementation/ethics.html - Privacy and data governance: https://publichealthaihandbook.com/implementation/privacy.html - Safety and monitoring: https://publichealthaihandbook.com/implementation/safety.html - Deployment: https://publichealthaihandbook.com/implementation/deployment.html - AI toolkit for public health: https://publichealthaihandbook.com/practical/toolkit.html - Policy and governance: https://publichealthaihandbook.com/future/policy.html Citation: Tegomoh, B. (2025). The Public Health AI Handbook: Evaluating AI Tools for Public Health Practice. DOI: 10.5281/zenodo.18263442. URL: publichealthaihandbook.com